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Zenegra User Essentials: Effects, Caution, Instructions

Zenegra (generic sildenafil) is an optimal cost-effective solution against ED. The health benefits and tips for effective and safe use.

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Contraindications

Zenegra (sildenafil citrate) is a drug whose history goes back to early 90s, with the safety profile being proven by dozens of patient-years.

Phosphodiesterase inhibitors, to which sildenafil belongs, are drugs with the mechanism promoting the vasodilation of the corpus cavernosum and therefore the erection. Therefore, they are vascular drugs. And as such, they must be well managed, with patients being careful about the doses and the general use.

It is true that these drugs, being vasodilators (and in fact among the side effects, in healthy subjects, it will be possible to observe facial flushing and headaches both from vasodilation) may lower the pressure a little. This helps to understand why one must have a certain caution in particular if taking nitrates, drugs which will strengthen the already robust hypotensive effects making their simultaneous assumption incompatible.

Zenegra and other drugs

The cardiopathic patient, especially if suffering from ischemic heart disease, are most commonly prescribed nitrates (examples: Monoket, Nitrosorbide, plasters such as Nitrachet or Nitroderm or others or, as needed, sublingual Carvasin). All these drugs, based on nitrosorbide (nitrates), have a summative effect of vasodilation with the possibility of acute hypotension (cardiovascular collapse) and hypoperfusion of all tissues, including the myocardium, with even fatal consequences. Caution must also be taken by patients with aortic stenosis or hypertrophic obstructive cardiomyopathy (rare and dangerous diseases) in which Zenegra can be dangerous even without association with nitrates.

A minimum of attention must also be paid when using hypotensive drugs such as a-blockers (doxazosine, terazosine or others with commercial names such as Cardura, Dredalen, Benur, etc.), often used for prostatic enlargement as well as for treating hypertension, whose association, once again, can lead to poorly tolerated hypotension.

Zenegra and cardiac conditions

Finally the "love pills" are contraindicated in patients with severe arterial hypotension (<90/50 mmHg), severe hepatic impairment (cirrhosis), with recent history of stroke or myocardial infarction (this latter in the history of the past 6 months), with degenerative retinal disorders such as retinitis pigmentosa. It therefore becomes essential to make a distinction between patients with stable and unstable heart disease.

Patients with stable heart disease for at least one to three months (ie an ischemia no more recent than this period), asymptomatic for angina, breathlessness, palpitations or other, can take the drug. If you are undergoing the treatment with nitrates, you must suspend them for 12-24 hours (obviously subject to medical authorization).
The patient with heart failure, unstable angina, tachyarrhythmia or other, especially if treated with nitroderivatives, should not take Zenegra, postponing the intake to better times. With these precautions, and always consulting with the andrologist and cardiologist, the erectogenic pills will have only positive effect on the heart condition, in every sense.